Vice President, Medical Affairs

Primary Responsibilities

Define and lead the global Medical Affairs strategy across Lexeo’s portfolio, ensuring alignment with development milestones and business objectives
Build, mentor, and lead a high-performing Medical Affairs organization, including external partners and future in-house team members
Own scientific communications strategy, including publications planning, congress strategy, medical education, and dissemination of clinical and disease-state insights
Establish and oversee external engagement strategy with key opinion leaders, investigators, medical societies, and patient advocacy organizations
Serve as the senior Medical Affairs representative in cross-functional governance, partnering with Clinical Development, Regulatory, Market Access, and Patient Advocacy leaders
Guide medical input into clinical development plans, patient identification strategies, launch readiness planning, and evidence-generation priorities
Oversee medical review processes and ensure high-quality, compliant externally facing scientific content and response materials
Lead advisory board strategy and execution, translating stakeholder insights into actionable plans for development and commercialization
Represent Lexeo externally at major scientific meetings, investigator forums, and executive-level partner interactions
Drive the development of onboarding, scientific training, and internal medical education initiatives to elevate organizational disease-area expertise
Lead medical evidence generation and align the same with company objectives 

Required Skills and Qualifications

Advanced degree in life sciences, medicine, or a related field required (MD, PharmD, PhD preferred) with 10+ years of industry experience
Significant Medical Affairs leadership experience in biotechnology or pharmaceuticals, with demonstrated progression in scope and responsibility
Deep expertise in scientific communications, external expert engagement, medical strategy, and cross-functional collaboration
Experience building or scaling Medical Affairs capabilities in a growth-stage organization, especially on transitioning from clinical stage to commercialization, is strongly preferred
Strong executive presence with excellent written and verbal communication skills and the ability to influence senior internal and external stakeholders
Ability to operate strategically while remaining hands-on in a fast-paced, evolving environment
Experience with real world datasets and studies
A working knowledge of how to incorporate artificial intelligence and machine learning principles into medical affairs