Periodic Labs · San Francisco
Manufacturing & OperationsScienceFullTime
We’re an AI and physical sciences company building state-of-the-art models to accelerate breakthroughs across materials, energy, and beyond. Backed by world-class investors and growing rapidly, we operate at the pace the frontier requires. Our team brings deep expertise, genuine ownership, and an insatiable drive to push the boundaries of what’s scientifically possible.
Periodic Labs is building an AI that can simulate science and verify its own predictions — training on the full scientific method. Central to that mission is a high-throughput experimental materials science lab that handles hazardous chemistries, high-pressure and high-temperature processes, air-sensitive synthesis, toxic gas exposure risks, and an expanding suite of thin-film deposition tools including PVD, PLD and the complexity of what we run overnight and autonomously is increasing every month.
We believe EHS is integral to this ambition, not a compliance function bolted on after the fact, but a core design discipline that makes autonomous science possible. This EHS role and the person will build our safety architecture, defining permitting strategy, designing life safety systems, conducting process hazard analyses, and ultimately training our AI to reason about risk during experimental planning and execution.
Own and manage all permitting processes with local, state, and federal agencies: Fire Department/CUPA via Accela, CERS submissions for hazardous materials, AQMD/BAAQMD air permits, and TSDF coordination for hazardous waste.
Maintain and update chemical inventory systems, SDS library, and hazard labeling in compliance with OSHA, CalEPA, and permitted MAQ thresholds including managing the expansion of our chemical inventory as new thin-film processes introduce HF-based wet chemistry, fluoride compounds, and specialty gases.
Lead Hazard Communication (HazCom) and SDS training programs for lab staff, including night shift and autonomous overnight operation protocols.
Coordinate EHS inspections and maintain required documentation and postings across both the existing powder lab and thin-film facility.
Design and review life safety systems, including fire suppression, e-stop networks, gas detection (including toxic gas alarms for HF, H2Se, and other process chemistries), interlocks, alarm interfaces, and emissions/waste abatement systems such as baghouses and scrubbers.
Conduct and document HAZOPs, PHA/FMEA, and risk assessments for new processes and lab systems, including high-pressure furnace operations, glovebox workflows, and thin-film deposition platforms.
Establish operational readiness and laboratory reliability systems for autonomous operations, including pre-startup safety reviews (PSSR), commissioning validation, alarm rationalization, startup/shutdown procedures, and critical equipment inspection programs.
Partner with automation and controls teams to implement machine safeguarding, fail-safes, interlocks, robotics safety controls, functional safety validation, safety PLC reviews, and automated motion hazard assessments for autonomous experimental systems.
Collaborate with ML/AI engineers on training an LLM to reason through process hazards, risk assessments, and safety constraints during experimental planning and autonomous execution — making EHS a first-class input to our AI’s decision-making.
Lead the site EH&S team through a hands-on approach to problem solving and operational support while promoting a strong safety and environmental culture. Ensure compliance with applicable EH&S regulations and standards, develop and improve programs aligned with company goals, and actively partner with lab and operations teams on day-to-day safety challenges. Own the digital EHS infrastructure, integrating inspections, training records, incident reporting, compliance tracking, KPI dashboards, action-item tracking, and audit workflows into a unified operational safety platform.
10+ years of experience in EHS, process safety, or chemical operations in labs, pilot plants, or manufacturing environments preferably in solid-state chemistry, materials science processing, or lab automation.
Strong knowledge of EH&S regulations, standards, and best practices.
Hands-on experience conducting HAZOPs or FMEAs and designing or reviewing functional safety systems.
Certification in EH&S (e.g., Certified Safety Professional, Certified Industrial Hygienist) is a plus.
Comfort working on-site in a fast-paced, high-complexity lab environment where experiments run 24/7 and the hazard profile evolves as new processes and equipment are introduced.
Experience designing EHS systems for autonomous or semi-autonomous lab environments where processes run without continuous human supervision.
Background supporting the build-out of a new laboratory facility, including coordinating permitting and safety system design in parallel with construction.
Familiarity with AI or ML tools as applied to risk assessment, safety documentation, or experimental planning or genuine curiosity about how to apply them.
Active participation in technical committees contributing to OSHA, NFPA, or IEC standard development.
Demonstrated accomplishments recognized in your field.
Minimum education: Bachelor’s degree or similar experience
Location: Menlo Park, CA or Montreal, Canada. (Soon: San Francisco, too)
Compensation: $200,000–$250,000 + equity
Visa sponsorship: Yes, we sponsor visas.
We’re building a team of the world’s best: the scientists, engineers, and problem-solvers who don’t just follow the frontier, they define it. If you’re driven to bring AI to life in the physical world and make discoveries that have never been made before, you belong here.